A fluorescent probe for rapid detection of hydrogen sulfide in blood plasma and brain tissues in mice

Yong Qian(Institute of Chemistry), Ling Zhang(Xuzhou Medical College), Shuting Ding(Nanjing University), Xin Deng(University of Chicago), Chuan He(University of Chicago), Xi Zheng(Institute of Chemistry), Hai-Liang Zhu(Nanjing University), Jing Zhao(Nanjing University)
Chemical Science
January 1, 2012
Cited by 189

Abstract

We describe the design, synthesis and application of a sensitive, selective, and fast fluorescent probe for H2S detection. A linear relationship between emission intensity and sulfide concentration was observed in biological bovine plasma systems. With this probe, we were able to estimate the sulfide concentration in mouse blood plasma and brain tissues.


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