Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy
Kevin J. Frankowski(University of Kansas), Jeffrey Aubé(University of Kansas), Laura Bohn(Scripps Research Institute), Marc G. Caron(Duke University), Shenghua Shi(Sanford Burnham Prebys Medical Discovery Institute), Layton H. Smith(Sanford Burnham Prebys Medical Discovery Institute), Santosh Hariharan(Pfizer (United States)), Stefan Vasile(Sanford Burnham Prebys Medical Discovery Institute), Thomas E. Prisinzano(University of Kansas), John M. Streicher(University of Arizona), Frank J. Schoenen(University of Kansas), Arianna Mangravita-Novo(Sanford Burnham Prebys Medical Discovery Institute), Palak Gosalia(Sanford Burnham Prebys Medical Discovery Institute), Kelin Li(University of Kansas), Ying Su(Sanford Burnham Prebys Medical Discovery Institute), Michael Vicchiarelli(Sanford Burnham Prebys Medical Discovery Institute), Susanne Heynen‐Genel(Sanford Burnham Prebys Medical Discovery Institute), Wilson Gray(Sanford Burnham Prebys Medical Discovery Institute), Lawrence S Barak(Duke University), Partha Ghosh(University of Kansas), Loribelle Milan(Sanford Burnham Prebys Medical Discovery Institute), Michael P. Hedrick(Sanford Burnham Prebys Medical Discovery Institute), Eduard Sergienko(Sanford Burnham Prebys Medical Discovery Institute), David A. Whipple(University of Kansas), Thomas D.Y. Chung(Sanford Burnham Prebys Medical Discovery Institute)
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