mTOR is a key modulator of ageing and age-related diseaseSimon C. Johnson(University of Washington), Peter S. Rabinovitch(Seattle University), Matt Kaeberlein(Guangdong Medical College)NatureJanuary 15, 201310.1038/nature11861Cited by 1,678SaveCiteExport RISWatch citationsAbstractRelated PapersAutophagy fights disease through cellular self-digestionNoboru Mizushima, Beth Levine, Ana María Cuervo et al.|Nature|2008|6.4kCaloric Restriction Delays Disease Onset and Mortality in Rhesus MonkeysRicki J. Colman, Rozalyn M. Anderson, Sterling C. Johnson et al.|Science|2009|2.3kmTOR controls mitochondrial oxidative function through a YY1–PGC-1α transcriptional complexJohn T. Cunningham, Joseph T. Rodgers, Daniel H. Arlow et al.|Nature|2007|1.5kAblation in Mice of the mTORC Components raptor, rictor, or mLST8 Reveals that mTORC2 Is Required for Signaling to Akt-FOXO and PKCα, but Not S6K1David A. Guertin, Deanna M. Stevens, Carson C. Thoreen et al.|Developmental Cell|2006|1.4kA Role for Autophagy in the Extension of Lifespan by Dietary Restriction in C. elegansMalene Bredahl Hansen, Abha Chandra, Laura L. Mitic et al.|PLoS Genetics|2008|764