A Bactericidal Effect for Human Lactoferrin
Roland R. Arnold(University of Alabama at Birmingham), Michael F. Cole(University of Alabama at Birmingham), Jerry R. McGhee(University of Alabama at Birmingham)
Cited by 684
Abstract
Streptococcus mutans and Vibrio cholerae, but not Escherichia coli, were killed by incubation with purified human apolactoferrin. Concentrations of lactoferrin below that necessary for total inhibition resulted in a marked reduction in viable colony-forming units. This bactericidal effect was contingent upon the metal-chelating properties of the lactoferrin molecule.
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