Interleukin-12 and the regulation of innate resistance and adaptive immunityGiorgio Trinchieri(Immune Regulation (United Kingdom))Nature reviews. ImmunologyJanuary 31, 200310.1038/nri1001Cited by 3,882SaveCiteExport RISWatch citationsAbstractRelated PapersIn the absence of endogenous IL-10, mice acutely infected with Toxoplasma gondii succumb to a lethal immune response dependent on CD4+ T cells and accompanied by overproduction of IL-12, IFN-γ and TNF-αRicardo T. Gazzinelli, Maria Wysocka, Sara Hieny et al.|The Journal of Immunology|1996|928Parasite-induced IL-12 stimulates early IFN- <i>gamma</i> synthesis and resistance during acute infection with <i>Toxoplasma gondii</i> .Ricardo T. Gazzinelli, Maria Wysocka, Seiji Hayashi et al.|The Journal of Immunology|1994|716Interleukin-18: A Novel Cytokine That Augments Both Innate and Acquired ImmunityHaruki Okamura, Hiroko Tsutsui, Shin‐ichiro Kashiwamura et al.|Advances in immunology|1998|454Development of Th1-type immune responses requires the type I cytokine receptor TCCRQi Chen, Nico Ghilardi, Hua Wang et al.|Nature|2000|399Molecular Mechanisms of the Induction of IL-12 and Its Inhibition by IL-10Miguel Aste-Amézaga, Xiaojing Ma, Alexandrina Sartori et al.|The Journal of Immunology|1998|391