Temporary Abolition of Pain in Man

Patrick D. Wall(Massachusetts Institute of Technology), William H. Sweet(Harvard University)
Science
January 6, 1967
Cited by 964

Abstract

In eight patients with intense chronic cutaneous pain, sensory nerves or roots. supplying the painful area were stimulated. Square-wave 0.1-millisecond pulses at 100 cycles per second were applied, and the voltage was raised until the patient reported tingling in the area. During this stimulation, pressure on previously sensitive areas failed to evoke pain. Four patients, who had diseases of their peripheral nerves, experienced relief of their pain for more than half an hour after stimulation for 2 minutes.


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