Pim-1 Kinase Phosphorylates and Stabilizes 130 kDa FLT3 and Promotes Aberrant STAT5 Signaling in Acute Myeloid Leukemia with FLT3 Internal Tandem Duplication

Karthika Natarajan(Center for Drug Evaluation and Research), Maria R. Baer(U-M Rogel Cancer Center)

PLoS ONE

September 5, 2013

10.1371/journal.pone.0074653

Cited by 74

Related Papers

Phase 3 study of the multidrug resistance modulator PSC-833 in previously untreated patients 60 years of age and older with acute myeloid leukemia: Cancer and Leukemia Group B Study 9720

|Blood|2002|365

Cyclosporin A Is a Broad-Spectrum Multidrug Resistance Modulator

|Clinical Cancer Research|2005|238

Outcome of older patients with acute myeloid leukemia

|Cancer|2013|197

Olverembatinib After Failure of Tyrosine Kinase Inhibitors, Including Ponatinib or Asciminib

|JAMA Oncology|2024|26

PP2A-activating Drugs Enhance FLT3 Inhibitor Efficacy through AKT Inhibition–Dependent GSK-3β–Mediated c-Myc and Pim-1 Proteasomal Degradation

|Molecular Cancer Therapeutics|2021|25