Copper as a Biocidal Tool

Gadi Borkow(Cupron (Israel)), Jeffrey Gabbay
Current Medicinal Chemistry
August 1, 2005
Cited by 716

Abstract

Copper ions, either alone or in copper complexes, have been used to disinfect liquids, solids and human tissue for centuries. Today copper is used as a water purifier, algaecide, fungicide, nematocide, molluscicide as well as an antibacterial and anti-fouling agent. Copper also displays potent anti-viral activity. This article reviews (i) the biocidal properties of copper; (ii) the possible mechanisms by which copper is toxic to microorganisms; and (iii) the systems by which many microorganisms resist high concentrations of heavy metals, with an emphasis on copper. Keywords: bacteriostatic, gram-negative organisms, electroplated coatings, copper-impregnated fabrics, water purifier, antiviral, oxidizing agents, cell membrane, cell viability


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