3D Bioprinting of Vascularized, Heterogeneous Cell‐Laden Tissue Constructs

David B. Kolesky(Harvard University), Ryan L. Truby(Harvard University), A. Sydney Gladman(Harvard University), Travis A. Busbee(Harvard University), Kimberly A. Homan(Harvard University), Jennifer A. Lewis(Harvard University)
Advanced Materials
February 18, 2014
Cited by 2,057Open Access
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Abstract

A new bioprinting method is reported for fabricating 3D tissue constructs replete with vasculature, multiple types of cells, and extracellular matrix. These intricate, heterogeneous structures are created by precisely co-printing multiple materials, known as bioinks, in three dimensions. These 3D micro-engineered environments open new ­avenues for drug screening and fundamental studies of wound healing, angiogenesis, and stem-cell niches. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.


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