Rigid, Self‐Assembled Hydrogel Composed of a Modified Aromatic Dipeptide

A. Mahler(Tel Aviv University), Meital Reches(Tel Aviv University), Meirav Rechter(Tel Aviv University), Smadar Cohen(Ben-Gurion University of the Negev), Ehud Gazit(Tel Aviv University)
Advanced Materials
April 25, 2006
Cited by 806

Abstract

A simple dipeptide self-assembles into a biocompatible hydrogel (see figure and inside cover). This novel biomaterial is extremely simple to prepare and has a remarkable rigidity. It is very stable under extreme conditions, can be injected, and can be shaped according to the vessel it has been assembled in. The hydrogel allows a wide variety of possible biomedical applications including tissue engineering, axonal regeneration, and controlled drug release.


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