Kinesin spindle protein (KSP) inhibitors. Part V: Discovery of 2-propylamino-2,4-diaryl-2,5-dihydropyrroles as potent, water-soluble KSP inhibitors, and modulation of their basicity by β-fluorination to overcome cellular efflux by P-glycoprotein
Christopher D. Cox(United States Military Academy), George D. Hartman(United States Military Academy), Matthew M. Zrada(United States Military Academy), Paul J. Coleman(Merck & Co., Inc., Rahway, NJ, USA (United States)), Robert B. Lobell(United States Military Academy), Marc Abrams(Thomas Jefferson University), Nancy E. Kohl(United States Military Academy), Kelly Hamilton(United States Military Academy), Eileen S. Walsh(United States Military Academy), R. M. Garbaccio(Merck & Co., Inc., Rahway, NJ, USA (United States)), Vicki J. South(United States Military Academy), David B. Whitman(United States Military Academy), Carolyn A. Buser(United States Military Academy), Michael J. Breslin(United States Military Academy), Mark E. Fraley(United States Military Academy), Weikang Tao(Jiangsu Hengrui Medicine (China)), Hans E. Huber(United States Military Academy)
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