Catalytic Control in the EGF Receptor and Its Connection to General Kinase Regulatory Mechanisms

Natalia Jura(QB3), John Kuriyan(Vanderbilt University), Markus A. Seeliger(Howard Hughes Medical Institute), Nicholas Endres(QB3), Thomas H. Schindler(University Hospital of Geneva), Xuewu Zhang(Southwestern Medical Center)

Molecular Cell

April 1, 2011

10.1016/j.molcel.2011.03.004

Cited by 307

Related Papers

Crystallographic <i>R</i> Factor Refinement by Molecular Dynamics

|Science|1987|2k

Structural Mechanism for STI-571 Inhibition of Abelson Tyrosine Kinase

|Science|2000|1.8k

The Conformational Plasticity of Protein Kinases

|Cell|2002|1.8k

An Allosteric Mechanism for Activation of the Kinase Domain of Epidermal Growth Factor Receptor

|Cell|2006|1.6k

Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia

|Cancer Cell|2002|1.6k