Metastatic tumors of the skin

Abstract

The clinical and pathologic features of cutaneous metastasis were studied in 724 patients, with histopathologic confirmation of both the primary tumors and the secondary lesions in the skin. Cutaneous metastatic lesions from carcinoma of the lung and kidney were usually found in men, were often recognized before the primary tumor, and appeared in almost every area of the skin surface. Metastasis from carcinoma of the breast to the skin occurred almost exclusively in women, tended to be localized to the anterior chest wall, and was usually found after the primary tumor. Most cutaneous lesions metastasizing from squamous cell carcinoma of the oral cavity were found on the face or neck of men in whom there was previous histologic documentation of the primary tumor.