Efficient and Selective Nickel-Catalyzed Addition of H−P(O) and H−S Bonds to Alkynes
Li‐Biao Han(National Institute of Advanced Industrial Science and Technology), Chen Zhang(National Institute of Advanced Industrial Science and Technology), Hideaki Yazawa(National Institute of Advanced Industrial Science and Technology), Shigeru Shimada(National Institute of Advanced Industrial Science and Technology)
Cited by 252
Abstract
The cheap nickel catalysts are more reactive than the corresponding noble metal catalysts in the catalytic additions of a variety of P(O)-H bonds and an S-H bond to alkynes, affording regio- and stereoselectively both the Markovnikov and the anti-Markovnikov adducts, respectively, in high yields. A related five-coordinate hydrido nickel complex in the catalysis is successfully isolated, which can react readily with an alkyne to give the addition products.
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