Identification of a Small Molecule Inhibitor of the IL-2/IL-2Rα Receptor Interaction Which Binds to IL-2

Abstract

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTIdentification of a Small Molecule Inhibitor of the IL-2/IL-2Rα Receptor Interaction Which Binds to IL-2Jefferson W. Tilley, Li Chen, David C. Fry, S. Donald Emerson, Gordon D. Powers, Denise Biondi, Tracey Varnell, Richard Trilles, Robert Guthrie, Francis Mennona, Gerry Kaplan, Ronald A. LeMahieu, Mathew Carson, Ru-Jen Han, C.-M. Liu, Robert Palermo, and Grace JuView Author Information Roche Research Center, Hoffmann-La Roche Inc. Nutley, New Jersey 07110 Cite this: J. Am. Chem. Soc. 1997, 119, 32, 7589–7590Publication Date (Web):August 13, 1997Publication History Received4 March 1997Revised27 May 1997Published online13 August 1997Published inissue 1 August 1997https://pubs.acs.org/doi/10.1021/ja970702xhttps://doi.org/10.1021/ja970702xrapid-communicationACS PublicationsCopyright © 1997 American Chemical SocietyRequest reuse permissionsArticle Views1362Altmetric-Citations107LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Assays,Inhibition,Inhibitors,Molecular interactions,Receptors Get e-Alerts