Kemp elimination catalysts by computational enzyme design

Daniela Röthlisberger(University of Washington), Olga Khersonsky, Andrew M. Wollacott, Lin Jiang, Jason DeChancie(University of California, Los Angeles), Jamie L. Betker(Howard Hughes Medical Institute), Jasmine L. Gallaher(Howard Hughes Medical Institute), Eric A. Althoff, Alexandre Zanghellini, Orly Dym(Weizmann Institute of Science), Shira Albeck(Weizmann Institute of Science), K. N. Houk(University of California, Los Angeles), Dan S. Tawfik, David Baker(Howard Hughes Medical Institute)
Nature
March 19, 2008
10.1038/nature06879
Cited by 1,314Open Access
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