Functional analysis of beta-secretase using mutagenesis and structural homology modeling
Lisa McConlogue(Gladstone Institutes), Gwen Tatsuno(Sunesis (United States)), Nobuyuki Ota(Howard Hughes Medical Institute), David A. Agard(University of California, San Francisco)
Cited by 3
Related Papers
Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein
|Nature|1995|2.5k
High-Level Neuronal Expression of Aβ<sub>1–42</sub>in Wild-Type Human Amyloid Protein Precursor Transgenic Mice: Synaptotoxicity without Plaque Formation
|Journal of Neuroscience|2000|1.9k
Mutation of the β-amyloid precursor protein in familial Alzheimer's disease increases β-protein production
|Nature|1992|1.8k
Plaque-independent disruption of neural circuits in Alzheimer’s disease mouse models
|Proceedings of the National Academy of Sciences|1999|1.1k