A single thiazole orange molecule forms an exciplex in a DNA i-motif
Baochang Xu(Nanyang Technological University), Xiangyang Wu(Nanyang Technological University), Edwin K. L. Yeow(Nanyang Technological University), Fangwei Shao(Nanyang Technological University)
Cited by 28
Abstract
A fluorescent exciplex of thiazole orange (TO) is formed in a single-dye conjugated DNA i-motif. The exciplex fluorescence exhibits a large Stokes shift, high quantum yield, robust response to pH oscillation and little structural disturbance to the DNA quadruplex, which can be used to monitor the folding of high-order DNA structures.
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