Presenilin-1 D257A and D385A Mutants Fail to Cleave Notch in Their Endoproteolyzed Forms, but Only Presenilin-1 D385A Mutant Can Restore Its γ-Secretase Activity with the Compensatory Overexpression of Normal C-terminal Fragment

Hangun Kim(Chonnam National University), Kwonseop Kim(Chonnam National University)
Journal of Biological Chemistry
March 30, 2005
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