YAP inhibits squamous transdifferentiation of Lkb1-deficient lung adenocarcinoma through ZEB2-dependent DNp63 repression

Yijun Gao(Shanghai Institutes for Biological Sciences), Wenjing Zhang(Shanghai Institutes for Biological Sciences), Xiangkun Han(Chinese Academy of Sciences), Fuming Li(Chinese Academy of Sciences), Xujun Wang(Tongji University), Rui Wang(Fudan University Shanghai Cancer Center), Zhaoyuan Fang(Chinese Academy of Sciences), Xinyuan Tong(Chinese Academy of Sciences), Shun Yao(Chinese Academy of Sciences), Fei Li(Chinese Academy of Sciences), Yan Feng(Chinese Academy of Sciences), Yihua Sun(Fudan University Shanghai Cancer Center), Yingyong Hou(Sun Yat-sen University), Zhongzhou Yang(Model Animal Research Center), Kun‐Liang Guan(University of California San Diego), Haiquan Chen(Thoracic Surgery Foundation), Lei Zhang(Chinese Academy of Sciences), Hongbin Ji(Chinese Academy of Sciences)
Nature Communications
August 13, 2014
10.1038/ncomms5629
Cited by 123Open Access
Full Text

Abstract

Related Papers

Genotypic and Histological Evolution of Lung Cancers Acquiring Resistance to EGFR Inhibitors
Lecia V. Sequist, Belinda A. Waltman, Dora Dias‐Santagata et al.|Science Translational Medicine|2011|3.6k
The Hippo pathway and human cancer
Kieran F. Harvey, Xiaomeng Zhang, David M. Thomas|Nature reviews. Cancer|2013|1.9k
Glioblastoma stem-like cells give rise to tumour endothelium
Rong Wang, Kalyani Chadalavada, Jennifer A. Wilshire et al.|Nature|2010|1.2k
The Hippo Signaling Pathway Components Lats and Yap Pattern Tead4 Activity to Distinguish Mouse Trophectoderm from Inner Cell Mass
Noriyuki Nishioka, Ken‐ichi Inoue, Kenjiro Adachi et al.|Developmental Cell|2009|1.1k
Mst1 and Mst2 Maintain Hepatocyte Quiescence and Suppress Hepatocellular Carcinoma Development through Inactivation of the Yap1 Oncogene
Dawang Zhou, Claudius Conrad, Fan Xia et al.|Cancer Cell|2009|935