Selective A<sub>1</sub>-Antagonists for Treatment of Cognitive Deficits
G. Schingnitz(Boehringer Ingelheim (Germany)), U. Küfner-Mühl(Boehringer Ingelheim (Germany)), Helmut A. Ensinger(Boehringer Ingelheim (Germany)), E. Lehr(Boehringer Ingelheim (Germany)), F J Kuhn(Boehringer Ingelheim (Germany))
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Abstract
Abstract A novel compound, KFM 19, is introduced, which turned out to be a selective adenosine A1-antagonist with good bioavailability. Its pharmacological profile suggests a high therapeutic potential for dementia and related cognitive deficits.
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