Palladium-Catalyzed Cross-Coupling Reactions of Organoboron Compounds

Abstract

Until recently, organoboronic acids have been of limited use in organic synthesis due to their low reactivity for ionic reactions. During the past two decades; however, it has become increasingly clear that they are valuable reagents capable of undergoing many carbon-carbon bond formations in organic syntheses. In 1979, catalytic carbon-carbon bond formation, via transmetalation between organoboron compounds and palladium(II) halides, was found to proceed in the presence of a base.