A new structural alert for benzimidazoles: 2,6-Dimethylphenyl substituents increase mutagenic potential and time-dependent CYP3A4 inhibition risk
Young‐Shin Kwak, Michael H. Serrano‐Wu(Broad Institute), Cornelia J. Forster(Novartis (United States)), Leslie Bell, Aaron Kanter, Alan D. Neubert, Mithat Gunduz, Paul V. Szklennik, Pascal Stadelmann, Shari Bickford, Jenny Zhan, Bryan Stroup, Yongjin Gong, Thomas A. Gilmore, Monish Jain, Eric T. Gangl, Gary M. Coppola, Susanne Glowienke(Novartis (Switzerland))
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