Upregulation of the angiogenic factors PlGF, VEGF and their receptors (Flt-1, Flk-1/KDR) by TSH in cultured thyrocytes and in the thyroid gland of thiouracil-fed rats suggest a TSH-dependent paracrine mechanism for goiter hypervascularization
Giuseppe Viglietto(Magna Graecia University), M. Graziella Persico(University of Salerno), Iole Paoletti, Paola Bruni(University of Florence), Annunciata Romano(Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale"), Daniela Califano(Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale"), Gennaro Chiappetta(Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale"), Valeria Mauriello(Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale"), Giovanni Manzo(Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale"), Maria Giulia Galati(Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale"), Carmine T Lago(Institute of Genetics and Biophysics), Alfredo Fusco(Ceinge Biotecnologie Avanzate (Italy))
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