Fibrosis — A Common Pathway to Organ Injury and Failure

Don C. Rockey(Medical University of South Carolina), P. Darwin Bell(Medical University of South Carolina), Joseph A. Hill(The University of Texas Southwestern Medical Center)
New England Journal of Medicine
March 18, 2015
Cited by 1,389

Abstract

Fibrosis is a consequence of the inflammatory response. When fibrotic tissue becomes excessive, it can have diverse pathophysiological effects on a number of organ systems. The mechanisms underlying fibrosis and approaches to therapy are reviewed.


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