The ChEMBL bioactivity database: an update

A. Patrícia Bento(European Bioinformatics Institute), Anna Gaulton(European Bioinformatics Institute), Anne Hersey(European Bioinformatics Institute), Louisa J. Bellis(European Bioinformatics Institute), Jon Chambers(European Bioinformatics Institute), Mark Davies(European Bioinformatics Institute), Felix Krüger(European Bioinformatics Institute), Yvonne Light(European Bioinformatics Institute), Lora Mak(European Bioinformatics Institute), Shaun McGlinchey(European Bioinformatics Institute), Michał Nowotka(European Bioinformatics Institute), George Papadatos(European Bioinformatics Institute), Rita Santos(European Bioinformatics Institute), John P. Overington(European Bioinformatics Institute)
Nucleic Acids Research
November 7, 2013
10.1093/nar/gkt1031
Cited by 1,544Open Access
Full Text

Abstract

ChEMBL is an open large-scale bioactivity database (https://www.ebi.ac.uk/chembl), previously described in the 2012 Nucleic Acids Research Database Issue. Since then, a variety of new data sources and improvements in functionality have contributed to the growth and utility of the resource. In particular, more comprehensive tracking of compounds from research stages through clinical development to market is provided through the inclusion of data from United States Adopted Name applications; a new richer data model for representing drug targets has been developed; and a number of methods have been put in place to allow users to more easily identify reliable data. Finally, access to ChEMBL is now available via a new Resource Description Framework format, in addition to the web-based interface, data downloads and web services.

Related Papers

No related papers found

Powered by citation graph analysis