Cloning of human satellite III DNA: different components are on different chromosomes

Howard J. Cooke(Mary Lyon Centre at MRC Harwell), J. Roger Hindley(University of Bristol)
Nucleic Acids Research
January 1, 1979
Cited by 467Open Access
Full Text

Abstract

Two fragments cloned from purified human satellite III DNA do not cross-react with each other. One fragment, for which a partial sequence is reported, hybridises to satellite II as well as III and is shown to originate on chromosome 1. The other cloned fragment originates from the Y chromosome. This fragment has undergone considerable changes in size when cloned in lambda gt WES lambda B. Human satellite III is shown to consist of a number of non-cross-reacting sequences which nevertheless are related by the presence of closely spaced Hin F1 sites.


Related Papers