Formation of monodisperse bubbles in a microfluidic flow-focusing device
Piotr Garstecki(Harvard University), Irina Gitlin(Harvard University), Willow R. DiLuzio(Harvard University), George M. Whitesides(Harvard University), Eugenia Kumacheva(University of Toronto), Howard A. Stone(Harvard University)
Cited by 629
Abstract
This letter describes a method for generating monodisperse gaseous bubbles in a microfluidic flow-focusing device. The bubbles can be obtained in a range of diameters from 10 to 1000μm. The volume Vb of the bubbles scales with the flow rate q and the viscosity μ of the liquid, and the pressure p of the gas stream as Vb∝p∕qμ. This method allows simultaneous, independent control of the size of the individual bubbles and volume fraction of the dispersed phase. Under appropriate conditions, bubbles self-assemble into highly ordered, flowing lattices. Structures of these lattices can be adjusted dynamically by changing the flow parameters.
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