Recurrent somatic mutation of FAT1 in multiple human cancers leads to aberrant Wnt activation

Luc G.T. Morris; Andrew Kaufman; Yongxing Gong; Deepa Ramaswami; Logan A. Walsh; Şevin Turcan; Stephanie Eng; Kasthuri Kannan; Yilong Zou; Luke Peng; Victoria E Banuchi; Phillip Paty; Zhaoshi Zeng; Efsevia Vakiani; David B. Solit; Bhuvanesh Singh; Ian Ganly; Linda M. Liau; Timothy C. Cloughesy; Paul S. Mischel; Ingo K. Mellinghoff; Timothy A. Chan

doi:10.1038/ng.2538

Recurrent somatic mutation of FAT1 in multiple human cancers leads to aberrant Wnt activation

Luc G.T. Morris(Memorial Sloan Kettering Cancer Center), Andrew Kaufman(Memorial Sloan Kettering Cancer Center), Yongxing Gong(Memorial Sloan Kettering Cancer Center), Deepa Ramaswami(Memorial Sloan Kettering Cancer Center), Logan A. Walsh(Memorial Sloan Kettering Cancer Center), Şevin Turcan(Memorial Sloan Kettering Cancer Center), Stephanie Eng(Memorial Sloan Kettering Cancer Center), Kasthuri Kannan(Memorial Sloan Kettering Cancer Center), Yilong Zou(Memorial Sloan Kettering Cancer Center), Luke Peng(Memorial Sloan Kettering Cancer Center), Victoria E Banuchi(Memorial Sloan Kettering Cancer Center), Phillip Paty(Memorial Sloan Kettering Cancer Center), Zhaoshi Zeng(Memorial Sloan Kettering Cancer Center), Efsevia Vakiani(Memorial Sloan Kettering Cancer Center), David B. Solit(Memorial Sloan Kettering Cancer Center), Bhuvanesh Singh(Memorial Sloan Kettering Cancer Center), Ian Ganly(Memorial Sloan Kettering Cancer Center), Linda M. Liau(University of California, Los Angeles), Timothy C. Cloughesy(University of California, Los Angeles), Paul S. Mischel(University of California, Los Angeles), Ingo K. Mellinghoff(Memorial Sloan Kettering Cancer Center), Timothy A. Chan(Memorial Sloan Kettering Cancer Center)

Nature Genetics

January 27, 2013

10.1038/ng.2538

Cited by 363

Abstract

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