Structure Revision of Circumdatins A and B, Benzodiazepine Alkaloids Produced by Marine Fungus <i>Aspergillus ostianus</i>, by X-ray Crystallography

Ryuhei Okura(Tokushima University), Keijiro Kito(Tokushima University), Takashi Ooi(Tohoku Medical and Pharmaceutical University), Michio Namikoshi(Tokushima University), Takenori Kusumi(Tokushima University)
The Journal of Organic Chemistry
May 7, 2008
Cited by 62

Abstract

The structures of circumdatins A and B, pentacyclic alkaloids produced by Aspergillus ostianus, were revised from the previously reported betaine structures to unique oxepin ones by X-ray crystallography. The co-occurring known alkaloids, circumdatins D, E, and H, and a new compound reported here, circumdatin J, have a common framework.


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