Mechanism of activation and function of protein kinase B

Dario R. Alessi(University of Dundee), Philip Cohen(University of Dundee)

Current Opinion in Genetics & Development

February 1, 1998

10.1016/s0959-437x(98)80062-2

Cited by 751

Abstract

Related Papers

Mechanism of activation of protein kinase B by insulin and IGF‐1.

Dario R. Alessi, Mirjana Andjelković, B. Caudwell et al.|The EMBO Journal|1996|3k

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

Thomas Franke, Sung‐Il Yang, Tung O. Chan et al.|Cell|1995|2k

Expression of a Constitutively Active Akt Ser/Thr Kinase in 3T3-L1 Adipocytes Stimulates Glucose Uptake and Glucose Transporter 4 Translocation

Aimee D. Kohn, Scott A. Summers, Morris J. Birnbaum et al.|Journal of Biological Chemistry|1996|1.3k

Dual Role of Phosphatidylinositol-3,4,5-trisphosphate in the Activation of Protein Kinase B

David Stokoe, Leonard R. Stephens, Terry Copeland et al.|Science|1997|1.2k

Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases

Jongkyeong Chung, Calvin J. Kuo, Gerald R. Crabtree et al.|Cell|1992|1.2k