Myelination Inhibition Factor: Dissociation from Induction of Experimental Allergic Encephalomyelitis

Marian W. Kies(National Institute of Mental Health), Bernard F. Driscoll(National Institute of Mental Health), Fredrick J. Seil(Stanford University), Ellsworth C. Alvord(University of Washington)
Science
February 16, 1973
Cited by 58

Abstract

Sensitization of guinea pigs with purified myelin basic protein induces experimental allergic encephalomyelitis (EAE) but does not induce a serum factor which inhibits myelin formation in vitro. This factor, induced by some unidentified constituent of whole central nervous system tissue, should not be characterized as a component of "EAE serum."


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