ALS-causing SOD1 mutants generate vascular changes prior to motor neuron degeneration

Zhihui Zhong, Rashid Deane(University of Rochester Medical Center), Zarina S. Ali(University of Rochester Medical Center), Margaret Parisi(University of Rochester Medical Center), Yuriy Shapovalov(University of Rochester Medical Center), M. Kerry O’Banion(University of Rochester Medical Center), Konstantin Stojanovic(University of Rochester Medical Center), Abhay P. Sagare(University of Rochester Medical Center), Séverine Boillée(University of California, San Diego), Don W. Cleveland(University of California, San Diego), Berislav V. Zloković(University of Rochester Medical Center)
Nature Neuroscience
March 16, 2008
10.1038/nn2073
Cited by 465Open Access
Full Text

Abstract

Related Papers

Motor Neuron Degeneration in Mice that Express a Human Cu,Zn Superoxide Dismutase Mutation
Mark E. Gurney, Haifeng Pu, Arlene Y. Chiu et al.|Science|1994|4.1k
Onset and Progression in Inherited ALS Determined by Motor Neurons and Microglia
Séverine Boillée, Koji Yamanaka, Christian S. Lobsiger et al.|Science|2006|1.6k
ALS: A Disease of Motor Neurons and Their Nonneuronal Neighbors
Séverine Boillée, Christine Vande Velde, Don W. Cleveland|Neuron|2006|1.4k
Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration
Bert Oosthuyse, Lieve Moons, Erik Storkebaum et al.|Nature Genetics|2001|1k
Neurovascular mechanisms of Alzheimer's neurodegeneration
Berislav V. Zloković|Trends in Neurosciences|2005|928