Adenovirus-Associated Defective Virus Particles

Robert W. Atchison(University of Pittsburgh), Bruce C. Casto(University of Pittsburgh), William McD. Hammon(University of Pittsburgh)
Science
August 13, 1965
Cited by 971

Abstract

Small, DNA-containing particles were separated from preparations of a simian adenovirus. These particles differed antigenically from the adenovirus. Replication of the particles in cell cultures was obtained only when theywere inoculated simultaneously with adenoviruses. This suggests that these adenovirus-associated particles behave as defective viruses.


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