Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element-binding protein-2.
Jay D. Horton(Center for Human Genetics), Hitoshi Shimano(University of Tsukuba)
Cited by 707
Related Papers
SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver
|Journal of Clinical Investigation|2002|4k
Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European Atherosclerosis Society Consensus Panel
|European Heart Journal|2017|3.8k
Molecular mediators of hepatic steatosis and liver injury
|Journal of Clinical Investigation|2004|1.8k
Low-density lipoproteins cause atherosclerotic cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus statement from the European Atherosclerosis Society Consensus Panel
|European Heart Journal|2020|1.5k
Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a.
|Journal of Clinical Investigation|1996|818