Insertion of Arynes into σ Bonds

Diego Peña(Universidade de Santiago de Compostela), Dolores Pérez(Universidade de Santiago de Compostela), Enrique Guitián(Universidade de Santiago de Compostela)
Angewandte Chemie International Edition
May 3, 2006
Cited by 224

Abstract

Enjoying a revival: Following a quiet period, numerous reports have recently appeared regarding the insertion of arynes into σ bonds (see scheme) as a result of milder, high-yielding methods for generating arynes and the introduction of palladium catalysis into aryne chemistry. The methodology shows promise as a means of preparing complex ortho-disubstituted arenes.


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