Daily Rhythm in Tyrosine Concentration in Human Plasma: Persistence on Low-Protein Diets

Richard J. Wurtman(Massachusetts Institute of Technology), Chuan Chou(Massachusetts Institute of Technology), Christopher M. Rose(Massachusetts Institute of Technology)
Science
November 3, 1967
Cited by 59

Abstract

The concentration of tyrosine in the plasma of normal males varies diurnally. It is lowest (9.5 +/- 0.35 micrograms per milliliter) between 0130 and 0230 hours and rises to a peak of 16.2 +/- 0.82 micrograms per milliliter by 1030 hours. This rhythm persists when subjects are maintained for 2 weeks on a diet that is very low in protein.


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