Metformin induces lactate production in peripheral blood mononuclear cells and platelets through specific mitochondrial complex I inhibition
Sarah Piel(Düsseldorf University Hospital), Magnus J. Hansson(Medicon Village), Johannes K. Ehinger(Lund University), Eskil Elmér(Medicon Village)
Cited by 70
Related Papers
Update on Immunologic Therapy With Anti–CTLA-4 Antibodies in Melanoma: Identification of Clinical and Biological Response Patterns, Immune-Related Adverse Events, and Their Management
|Seminars in Oncology|2010|170
Cell-permeable succinate prodrugs bypass mitochondrial complex I deficiency
|Nature Communications|2016|153
Bioengineering and Semisynthesis of an Optimized Cyclophilin Inhibitor for Treatment of Chronic Viral Infection
|Chemistry & Biology|2015|38
Changes in energy metabolism due to acute rotenone-induced mitochondrial complex I dysfunction – An in vivo large animal model
|Mitochondrion|2016|27
Bioenergetic bypass using cell-permeable succinate, but not methylene blue, attenuates metformin-induced lactate production
|Intensive Care Medicine Experimental|2018|26