Alkaline Phosphatase Promotes Radioprotection and Accumulation of WR-1065 in V79-171 Cells Incubated in Medium Containing WR-2721

Paula M. Calabro-Jones(University of California San Diego), Robert C. Fahey(University of California San Diego), Geraldine D. Smoluk(University of California San Diego), John F. Ward(University of California San Diego)
International Journal of Radiation Biology and Related Studies in Physics Chemistry and Medicine
January 1, 1985
Cited by 168

Abstract

Addition of alkaline phosphatase and WR-2721 to culture medium containing V79-171 cells leads to production of WR-1065 and its disulphide forms in the medium, to cellular accumulation of WR-1065, and to radioprotection which correlates with cellular WR-1065 level.


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