CRISPR Inversion of CTCF Sites Alters Genome Topology and Enhancer/Promoter Function

Ya Guo; Quan Xu; Daniele Canzio; Jia Shou; Jinhuan Li; David U. Gorkin; Inkyung Jung; Haiyang Wu; Yanan Zhai; Yuanxiao Tang; Yichao Lu; Yonghu Wu; Zhilian Jia; Wei Li; Michael Q. Zhang; Bing Ren; Adrian R. Krainer; Tom Maniatis; Qiang Wu

doi:10.1016/j.cell.2015.07.038

CRISPR Inversion of CTCF Sites Alters Genome Topology and Enhancer/Promoter Function

Ya Guo(Shanghai Jiao Tong University), Quan Xu(Shanghai Jiao Tong University), Daniele Canzio(Columbia University Irving Medical Center), Jia Shou(Shanghai Jiao Tong University), Jinhuan Li(Shanghai Jiao Tong University), David U. Gorkin(University of California San Diego), Inkyung Jung(University of California San Diego), Haiyang Wu(Shanghai Jiao Tong University), Yanan Zhai(Shanghai Jiao Tong University), Yuanxiao Tang(Shanghai Jiao Tong University), Yichao Lu(Shanghai Jiao Tong University), Yonghu Wu(Shanghai Jiao Tong University), Zhilian Jia(Shanghai Jiao Tong University), Wei Li(Shanghai Jiao Tong University), Michael Q. Zhang(The University of Texas at Dallas), Bing Ren(University of California San Diego), Adrian R. Krainer(Cold Spring Harbor Laboratory), Tom Maniatis(Columbia University Irving Medical Center), Qiang Wu(Shanghai Jiao Tong University)

Cell

August 1, 2015

10.1016/j.cell.2015.07.038

Cited by 1,046Open Access

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