Clinical Significance of Cytogenetic Abnormalities in Adult Acute Lymphoblastic Leukemia
Stefan Faderl, Hagop M. Kantarjian(The University of Texas MD Anderson Cancer Center), Moshe Talpaz, Zeev Estrov(The University of Texas MD Anderson Cancer Center)
Cited by 302
Abstract
ACUTE LYMPHOBLASTIC leukemias (ALL) are characterized by clonal proliferation, accumulation, and tissue infiltration of neoplastic cells. They are mainly regarded as childhood diseases, with an early incidence peak at 2 to 5 years of age, where they represent about 80% of the childhood leukemias in
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