A Microbiologic Method for Detecting Folic Acid Deficiency in Man
Herman Baker(Haskins Laboratories), Victor Herbert(Haskins Laboratories), Oscar Frank(Haskins Laboratories), I. Pasher(Haskins Laboratories), S. H. Hutner(Haskins Laboratories), Louis R. Wasserman(Haskins Laboratories), Harry Sobotka(Haskins Laboratories)
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Abstract
Abstract A microbiologic method based on Lactobacillus casei for assaying folic acid activity in serum is presented. The assay correlates directly with the clinical diagnosis. Comparison with formimino-L-glutamic acid determinations and other microbiologic assay methods shows the assay here described to yield a more dependable estimate of the folic acid status in humans.
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