Gene targeting: a practical approach.

Abstract

Gene targeting vectors for mammalian cells, Paul Hasty and Allan Bradley production of targeted embryonic stem cell clones, Wolfgang Wurst and Alexandra L. Joyner analysis of gene transfer in bone marrow stem cells, Kateri A. Moore and John W. Belmont production of chimeras and genetically-defined offspring from targeted ES cells, Virginia Papiaoannou and Randall Johnson production of completely ES cell-derived foetuses, Andras Nagy and Janet Rossant gene and enhancer trap screens in ES cell chimeras, A. Gossler and J. Zachgo. Appendix: Suppliers of specialist items.