Clinical problem solving and diagnostic decision making: selective review of the cognitive literature

Abstract

can be expertly administered. 18 Ideally, as many patients as possible would be treated within 90 or 120 minutes of onset, when benefit is maximal.The time has come for proponents of thrombolysis and reformed thrombolytic contrarians to join together to improve systems of acute stroke care worldwide so that more properly evaluated, properly selected, and properly informed stroke patients can be treated with intravenous thrombolytics within three hours of onset.JLS, CSK, and SS have served as site investigators in acute stroke clinical trials sponsored by several (15, 11, and 17 respectively) pharmaceutical and biotechnology companies, including Genentech and Boehringer-Ingelheim; have received speaking honorariums from several (12, 5, 8) pharmaceutical companies, including Genentech and Boehringer-Ingelheim; and have served as consultants on scientific advisory boards for several (7, 1, 5) pharmaceutical and biotechnology companies developing acute stroke treaments, including Boehringer-Ingelheim and Genentech.