Functional significance of mitochondrial bound hexokinase in tumor cell metabolism. Evidence for preferential phosphorylation of glucose by intramitochondrially generated ATP.
Komal Arora(Johns Hopkins University), Peter L. Pedersen(University of Southern Denmark)
Cited by 319
Related Papers
Ion motive ATPases. I. Ubiquity, properties, and significance to cell function
|Trends in Biochemical Sciences|1987|966
Hexokinase II: Cancer's double-edged sword acting as both facilitator and gatekeeper of malignancy when bound to mitochondria
|Oncogene|2006|756
Tumor Mitochondria and the Bioenergetics of Cancer Cells
|Progress in tumor research|2015|715
The peripheral-type benzodiazepine receptor. Localization to the mitochondrial outer membrane.
|Journal of Biological Chemistry|1986|691
Hexokinase-2 bound to mitochondria: Cancer's stygian link to the “Warburg effect” and a pivotal target for effective therapy
|Seminars in Cancer Biology|2008|585