Diffuse Liver Metastasis of Small-Cell Lung Cancer Presenting as Acute Liver Failure and Diagnosed by Transjugular Liver Biopsy: A Rare Case in Whom Nodular Lesions Were Detected by Enhanced CT Examination

Saori Mishima(National Center for Global Health and Medicine), Yuichi Nozaki(National Center for Global Health and Medicine), Shintaro Mikami(National Center for Global Health and Medicine), E. Kihira(National Center for Global Health and Medicine), Motoyasu Iikura(National Center for Global Health and Medicine), Rikiya Koketsu(National Center for Global Health and Medicine), Haruhito Sugiyama(National Center for Global Health and Medicine), T. Masuda(National Center for Global Health and Medicine), Hikaru Kaname(National Center for Global Health and Medicine), Y. Egami(National Center for Global Health and Medicine), Toshinori Nakayama(National Center for Global Health and Medicine), Kanehiro Hasuo(National Center for Global Health and Medicine), Hiroki Nakamura(National Center for Global Health and Medicine), T Igari(National Center for Global Health and Medicine), Kazuhiro Watanabe(National Center for Global Health and Medicine), Naoyoshi Nagata(National Center for Global Health and Medicine), Toshiyuki Sakurai(National Center for Global Health and Medicine), Chizu Yokoi(National Center for Global Health and Medicine), Masao Kobayakawa(National Center for Global Health and Medicine), Yasushi Kojima(National Center for Global Health and Medicine), J. Akiyama(National Center for Global Health and Medicine), Masaru Imamura(National Center for Global Health and Medicine), Naohiko Masaki(National Center for Global Health and Medicine), M. Yanase(National Center for Global Health and Medicine)
Case Reports in Gastroenterology
April 1, 2015
Cited by 633Open Access
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Abstract

Small-cell lung cancer (SCLC) is a subgroup of lung cancer with a high frequency of liver metastasis, which is a predictor of poor prognosis. Diffuse liver metastases of SCLC with no visible nodular lesions in the liver when examined using computed tomography (CT) are relatively rare; however, a few cases with rapid progression to acute liver failure that were diagnosed after death have been reported. In this paper, we report a 63-year-old man with diffuse liver metastases of SCLC that were histologically diagnosed using a transjugular liver biopsy while the patient was alive, even though no lesions were visible during a contrast-enhanced CT examination.


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