The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals.

Yasuko Kureishi(St. Elizabeth's Medical Center), Zhengyu Luo(St. Elizabeth's Medical Center), Ichiro Shiojima(St. Elizabeth's Medical Center), Ann Bialik(Tufts University), David Fulton(Yale University), David J. Lefer(Louisiana State University Health Sciences Center Shreveport), William C. Sessa(Yale University), Kenneth Walsh(St. Elizabeth's Medical Center)
Nature Medicine
September 1, 2000
10.1038/79510
Cited by 1,434

Abstract

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