Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and γ-secretase activity

Michael S. Wolfe(University of Tennessee at Knoxville), Weiming Xia(Brigham and Women's Hospital), Beth L. Ostaszewski(Brigham and Women's Hospital), Thekla S. Diehl(Brigham and Women's Hospital), W. Taylor Kimberly(Brigham and Women's Hospital), Dennis J. Selkoe(Brigham and Women's Hospital)
Nature
April 1, 1999
10.1038/19077
Cited by 1,922

Abstract

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