<i>NEISSERIA GONORRHOEAE</i> I

Douglas S. Kellogg(United States Public Health Service), William L. Peacock(United States Public Health Service), W. E. Deacon(United States Public Health Service), Leonard Brown(United States Public Health Service), Carl I. Pirkle(United States Public Health Service)
Journal of Bacteriology
June 1, 1963
10.1128/jb.85.6.1274-1279.1963
Cited by 1,211Open Access
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Abstract

Kellogg, Douglas S., Jr. (Communicable Disease Center, Atlanta, Ga.), William L. Peacock, Jr., W. E. Deacon, L. Brown, and Carl I. Pirkle. Neisseria gonorrhoeae. I. Virulence genetically linked to clonal variation. J. Bacteriol. 85:1274-1279. 1963.-One type, obtained from the purulent exudate of acute gonorrhea was maintained by 69 selective in vitro passages, at which point the organisms produced infections in human volunteers. A predominance of clonal types found in laboratory strains and a lack of ability to infect human volunteers resulted from 69 nonselective in vitro passages. Physiological and serological characteristics of the clonal types are compared. We are now in a position to study Neisseria gonorrhoeae organisms in their virulent form.

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