Anatomy-specific classification of medical images using deep convolutional nets

Holger R. Roth(National Institutes of Health), Christopher T. Lee(National Institutes of Health), Hoo-Chang Shin(National Institutes of Health Clinical Center), Ari Seff(National Institutes of Health), Lauren Kim(National Institutes of Health), Jianhua Yao(National Institutes of Health), Le Lü(National Institutes of Health Clinical Center), Ronald M. Summers(National Institutes of Health)
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April 1, 2015
Cited by 182Open Access
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Abstract

Automated classification of human anatomy is an important prerequisite for many computer-aided diagnosis systems. The spatial complexity and variability of anatomy throughout the human body makes classification difficult. “Deep learning” methods such as convolutional networks (ConvNets) outperform other state-of-the-art methods in image classification tasks. In this work, we present a method for organ- or body-part-specific anatomical classification of medical images acquired using computed tomography (CT) with ConvNets. We train a ConvNet, using 4,298 separate axial 2D key-images to learn 5 anatomical classes. Key-images were mined from a hospital PACS archive, using a set of 1,675 patients. We show that a data augmentation approach can help to enrich the data set and improve classification performance. Using ConvNets and data augmentation, we achieve anatomy-specific classification error of 5.9 % and area-under-the-curve (AUC) values of an average of 0.998 in testing. We demonstrate that deep learning can be used to train very reliable and accurate classifiers that could initialize further computer-aided diagnosis.


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